Another concern with diethanolamine is its potential for contamination. Scorecard _ The Pollution Information Site. Ethanolamine was reported to be used in primarily in rinse-off hair products. TheCosmetic Ingredient Review(CIR), an independent expert scientific panel established by the Personal Care Products Council, has evaluated the safety of ethanolamine used in personal care products and cosmetics. These compounds have also been reviewed for safety by the Cosmetic Ingredient Review (CIR), an independent expert scientific panel established by the Personal Care Products Council, and by other scientific agencies. Cancer. Dimethylaminoethanol is used as a curing agent for polyurethanes and epoxy resins. DIETHANOLAMINE | Occupational Safety and Health Administration This claim has been assessed by both the. [7] Report on Carcinogens, Twelfth Edition (2011) Available Online: http://ntp.niehs.nih.gov/ntp/roc/twelfth/profiles/Nitrosamines.pdf. As with chemical reactions, there may be unavoidable small amounts of the starting materials carried into the final product. DEA is rarely used and when it is used it is used in very small quantities to ensure that the product is gentle and non-irritating. Like all Ethanolamines, Diethanolamine is produced industrially exclusively by the reaction of ethylene oxide with excess ammonia. Every product and ingredient in Skin Deep gets a two-part score one for hazard and one for data availability. The NTP develops, evaluates and disseminates scientific information about potentially toxic and hazardous chemicals. (2008). Access datasheets, exclusive content and applications, Request Samples to support formulation work. Triethanolammonium salts in some cases are more soluble than salts of alkali metals that might be used otherwise, and results in less alkaline products than would from using alkali metal hydroxides to form the salt. Available Online: http://www.annmariegianni.com/ingredient-watch-list-ethanolamines-mea-dea-tea%E2%80%94potential-carcinogens. TEA, DEA and Ethanolamine help to form emulsions by reducing the surface tension of the substances to be emulsified so that water-soluble and oil-soluble ingredients can be blended together. 2007. The ACC mark, Responsible Care, the hands logo mark, CHEMTREC, TRANSCAER, and americanchemistry.com are registered service marks of the American Chemistry Council, Inc. May also be known as: Monoethanolamine (MEA), Diethanolamine (DEA), Triethanolamine (TEA), U.S. Occupational Safety and Health Administration, U.S. Department of Labors Occupational Safety and Health Administration, there is no reason for consumers to be alarmed. DEA and DEA-related ingredients function as emulsifiers or foaming agents in cosmetics, or to adjust a product's pH (acidity). If a product is too acidic or too basic it can damage the integrity of this barrier. The Panel concluded that Triethanolamine and the related TEA-containing ingredients are safe in the present practices of use and concentration when formulated to be non-irritating. (2012). In 1983, the CIR Expert Panel evaluated the scientific data and concluded that TEA, DEA and Ethanolamine were safe for use in cosmetics and personal care products designed for discontinuous, brief use followed by thorough rinsing from the surface of the skin. Based on this data the determined that diethanolamine is safe for its indicated uses. FDA stated that the NTP study did not establish a link between DEA and the risk of cancer in humans. How to Avoid Toxins in Your Toothpaste: 12 Ingredients to Ditch Now In product formulations, diethanolamine can cause the formation of nitrosamines, which are by-products formed in production. Diethanolamine is used in many different products. EWG Skin Deep | What is DIETHANOLAMINE - Environmental Working Group Most jurisdictions limit the concentrations of diethanolamine that can be used in products to reduce the irritation and to minimise any prolonged side effects. What Is It? TEA has also been used in photographic (silver halide) processing. AOEC (Association of Occupational and Environmental Clinics). Diethanolamine - Cosmetics Info DEA is an ingredient in engine degreasers and industrial strength detergents. Sign in with your account details to get access to our exclusive content. An official website of the United States government, Recalls, Market Withdrawals and Safety Alerts, Per and Polyfluoroalkyl Substances (PFAS) in Cosmetics, ingredients that are prohibited or restricted by regulation, Key Legal Concepts: Interstate Commerce, Adulterated, and Misbranded. Find personal care, cleaning, and food products on the EWG Healthy Living app. Due to its emulsification properties, MEA and DEA also can be used in industrial applications, such as chemical manufacturing and gas treating. DEA is also used as a chemical intermediate in agrochemicals to make pesticides, where it helps increase a pesticides ability to dissolve in water. Accessed April 25, 2022. Often Diethanolamine is used in generic toothpaste formulations. TEA is used as a surfactant in agrochemicals to help pesticides disperse into crops. Instead, small amounts of DEA may be present in products as a residue in other ingredients, such as cocamide DEA, lauramide DEA and stearamide DEA, which are primarily used in rinse-off applications such as shampoos and hair dyes. TEA is used as a surfactant in agrochemicals, to help pesticides disperse into crops, which then helps repel insects from the crops. A program of Breast Cancer Prevention Partners, Home > Chemicals > Ethanolamine Compounds (MEA, DEA, TEA And Others). The 2001 an opinion issued by the EUs Scientific Committee for Cosmetic Products and Non-Food Products (SCCNFP; now known as the SCCS) stated that amines occur only in their salt form in all cosmetic products. Ethoxylation can lead to contamination with 1,4-dioxane, which is also a known carcinogen. Methyldiethanolamine, also known as N-methyl diethanolamine and more commonly as MDEA, is the organic compound with the formula CH 3 N(C 2 H 4 OH) 2.It is a colorless liquid with an ammonia odor. [11] Panchal, S. R., & Verma, R. J. Cosmetic Ingredient Review, Review of Triethanolamine, Diethanolamine, and Ethanolamine CIR. 2006. The hydrophilic liquid is used as a surfactant as well as a corrosion inhibitor. Amines may be incompatible with isocyanates . Diethanolamine (DEA) Added to toothpaste to create a greater foaming effect, diethanolamine (DEA) is a hormone disrupter. As an amine, it is mildly alkaline and reacts with acids to form salts or soaps. [13] Systemic and respiratory tract (RT) toxicity was analyzed for 28 days in a nose specific inhalation 2008 study in Wistar rats; TEOA seems to be less potent in regard to systemic toxicity and RT irritancy than diethanolamine (DEA). Diethanolamine is used in the production of salt of long-chain fatty acids, allowing hydrating products to be able to foam and lather. The Expert Panel suggested that all products that contain diethanolamine should be formulated to be non-irritating. Diethanolamine - Some Industrial Chemicals - NCBI Bookshelf It facilitates the grinding process by preventing agglomeration and coating of the powder at the surface of balls and mill wall.[6]. In pharmaceutics, triethanolamine is the active ingredient of some eardrops used to treat impacted earwax. Are you sure? This is why the pH of a product is so important. The Earth Day 2023 theme is invest in our planet, and products and technologies made possible by chemistry help to do just that, enabling advances in agriculture, water treatment, energy efficiency and more. PDF Diethanolamine - U.S. Environmental Protection Agency The U.S. EPA considers diethanolamine a hazardous air pollutant and has listed the substance on the Toxics Release Inventory (a compilation of substances that pose a threat to human or environmental health). Triethanolamine (TEA) is listed as Trialkylamines, trialkanolamines and their salts, and Ethanolamine is listed as Monoalkylamines, monoalkanolamines and their salts, in Annex III, Part I of the Cosmetics Regulationof the European Union. References:Cosmetic Ingredient Review, Review of Triethanolamine, Diethanolamine, and Ethanolamine CIR. Ingredients have been studied extensively. CIR has also issued separate safety evaluations for TEA, DEA, and MEA, stating that these chemicals are safe in their current uses and concentrations when formulated appropriately. THIS SITE IS FOR INFORMATIONAL PURPOSES ONLY AND SHOULD NOT BE USED AS A SUBSTITUTE FOR ADVICE OR TREATMENT FROM A QUALIFIED MEDICAL PROFESSIONAL. The use of cocamide DEA has decreased in recent years. DEA is used as an emulsifier in shampoos, cleaners, and detergents. Endocrine disruptors and asthma-associated chemicals in consumer products. If FDA determines that there is a possible risk from these ingredients, they will advise the industry and the public and will consider its legal options under the authority of the Food, Drug and Cosmetic Act in protecting the health and welfare of consumers., A study published in the FASEB scientific journal in 2006 raised concerns that Diethanolamine (DEA), an ingredient found in many shampoos and other personal care products, appears to interfere with normal brain development in baby mice when applied to the skin of pregnant mice. Although the report noted that DEA may be present in shampoos, DEA itself is rarely used in cosmetic or personal care products. Accessed April 25, 2022. In cosmetics and personal care products, these ingredients are used in the formulation of shampoos, hair dyes, bath products, and lotions. This claim has been tested by the, as well as the International Agency for Research on Cancer, part of the World Health Organization. The NTP study did not establish a link between DEA and the risk of cancer in humans. [8][9][10], A 1996 study found that triethanolamine (TEOA) occasionally causes contact allergy.